Research Areas
My research is focused on translational and precision medicine, integrating molecular biology, human genetics, computational biology, and clinical investigation to address complex human diseases. My work is organized into the following interconnected research areas:
Translational Medicine & Clinical Hemostasis
Focus: Sepsis, disseminated intravascular coagulation (DIC), thrombophilia, infective endocarditis, coagulation biomarkers.
This research area investigates the molecular and clinical mechanisms underlying coagulation abnormalities in systemic inflammatory and infectious diseases. My work examines the interaction between coagulation pathways, inflammation, and endothelial dysfunction, with particular emphasis on disseminated intravascular coagulation and thromboembolic complications. The goal is to identify clinically relevant biomarkers and molecular targets that can support early diagnosis, risk stratification, and personalized therapeutic strategies.
Reproductive Genetics & Genomic Medicine
Focus: Human infertility, spermatogenic failure, whole-exome sequencing, pathogenic variant discovery.
This line of research addresses the genetic basis of male and female infertility using genomic and molecular approaches. I apply whole-exome sequencing, variant prioritization, and genotype–phenotype correlation to identify pathogenic mutations associated with reproductive disorders. Functional interpretation of variants is supported by molecular biology and bioinformatic analyses to improve understanding of disease mechanisms and support precision reproductive medicine.
Computational Biology & Machine Learning
Focus: Artificial intelligence architectures, deep learning, explainable models, disease and protein prediction.
My computational research involves the development and application of machine-learning and deep-learning models for biomedical data analysis. This includes AI-based prediction of disease associations, protein function, peptide activity, and genomic variants. Emphasis is placed on explainable and interpretable models that enhance biological understanding while maintaining clinical relevance.
Environmental Health & Trace Element Analysis
Focus: Toxicology, trace elements, environmental exposure, endocrine-disrupting chemicals.
This research area explores the role of essential and toxic trace elements in human health and disease. I investigate elemental imbalances in biological samples and their association with cancer, reproductive disorders, metabolic conditions, and environmental exposure. The work integrates analytical chemistry, molecular biology, and epidemiological perspectives to assess environmental health risks.
Oncology, Pharmacology & Biotechnology
Focus: Drug repurposing, molecular docking, pharmacogenomics, translational oncology.
My work in oncology and pharmacology focuses on molecular mechanisms of cancer progression and therapeutic response. I employ in silico drug design, molecular docking, pharmacogenomic analysis, and biomarker discovery to support drug repurposing and targeted therapy development. This research aims to bridge molecular insights with translational and clinical applications.